An antimicrobial TiO2 coating for reducing hospital-acquired infection.
J Biomed Mater Res B Appl Biomater
; 85(1): 220-4, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-17854067
ABSTRACT
Titanium dioxide (TiO2) has been developed and applied extensively in the form of coatings, in particular for its unique properties such as non-toxicity, high photocatalytic activity, and strong self-cleaning ability. These coatings, which can be prepared via various processes, have not yet been proved to be antimicrobial. This research involves an arc ion plating method to produce TiO2 film on medical grade AISI 304 stainless steel. Antimicrobial efficacy of the deposits is expected due to the photocatalysis action of the anatase phase presented in the deposit. The performance of the coating is evaluated by a JIS Z28012000 industrial standard. Experimental results show that TiO2 film mainly consisting of anatase structure can be prepared with a high growth rate of 5 microm/h. Antimicrobial activity (R) of the deposited TiO2 film against Staphylococcus aureus and Escherichia coli was 3.0 and 2.5, respectively, far beyond the value designated in JIS standard. This provides an effective antimicrobial surface coating method for medical implements thereby reducing the risk of hospital-acquired infections.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Titânio
/
Infecção Hospitalar
/
Materiais Revestidos Biocompatíveis
/
Anti-Infecciosos
Tipo de estudo:
Evaluation_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Biomed Mater Res B Appl Biomater
Ano de publicação:
2008
Tipo de documento:
Article