Extracellular volume in preterm infants: influence of gestational age and colloids.
Early Hum Dev
; 27(1-2): 1-7, 1991 Nov.
Article
em En
| MEDLINE
| ID: mdl-1802656
ABSTRACT
We assessed the effect of fresh frozen plasma (FFP) on extracellular volume (ECV) during the first few days of life in two groups of preterm infants, group 1 (gestational age less than 30 weeks) and group 2 (gestational age 30-34 weeks). The infants were randomly assigned to one of two treatment groups, one receiving FFP, the other not; group 1 infants receiving no treatment (n = 8) and group 1 infants receiving FFP (n = 11), and group 2 infants receiving no treatment (n = 9) and group 2 receiving FFP (n = 10). FFP was given at a dose of 10 ml/kg daily during a two-hour period for the first three days of life. ECV was measured on day 1 before FFP was given and on day 4 by the distribution of bromide. There was a significant correlation between birth weight and initial ECV (r = 0.85, P less than 0.001). In group 1 ECV was significantly higher than in group 2 (P less than 0.02). In group 1 receiving no treatment mean weight loss and mean decrease in ECV were equal (84 g/kg and 78 ml/kg, respectively), but no correlation between the two parameters could be found (r = 0.68, P = 0.06). In the other study groups, mean weight loss was higher than mean decrease in ECV, with no correlation between weight loss and change in ECV.(ABSTRACT TRUNCATED AT 250 WORDS)
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Equilíbrio Hidroeletrolítico
/
Plaquetas
/
Recém-Nascido Prematuro
/
Transfusão de Componentes Sanguíneos
/
Espaço Extracelular
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Early Hum Dev
Ano de publicação:
1991
Tipo de documento:
Article