Computed tomography findings in urban transportation workers with low cumulative asbestos exposure.
Int J Tuberc Lung Dis
; 11(12): 1352-7, 2007 Dec.
Article
em En
| MEDLINE
| ID: mdl-18034958
ABSTRACT
OBJECTIVE:
To assess the frequency of computed tomography (CT) scan pleural and interstitial changes in a population of urban transportation workers with low cumulative exposure to asbestos, and to measure inter-reader agreement.DESIGN:
A total of 269 male volunteers (mean age 54.0 +/- 2.3 years, mean estimated cumulative exposure index 1.7 +/- 2.3 fibres/ml-years), underwent a CT scan which was read independently by three experienced readers, with further consensus reading in case of pleural or parenchymal abnormalities. Inter-reader agreement was assessed by means of Kappa statistic.RESULTS:
On consensus reading, four subjects had interstitial opacities, three had diffuse pleural thickening and 26 (9.7%) had pleural plaques that were unilateral in 65% of cases and < or =2 mm thick in 54% of cases. No correlation was observed between pleural plaques and latency, duration of exposure or cumulative exposure. The inter-reader agreement for the detection of pleural abnormalities was fair.CONCLUSION:
In this relatively young population with low cumulative exposure to asbestos, the prevalence of pleural abnormalities was low. These abnormalities were very limited in thickness and extent, leading to marked inter-reader variability and making it difficult to assess their relationship to asbestos exposure.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asbestose
/
Tomografia Computadorizada por Raios X
/
Exposição Ocupacional
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Int J Tuberc Lung Dis
Ano de publicação:
2007
Tipo de documento:
Article