[The anti-idiotypic response to the experimental administration of the inactivated or live influenza virus]. / Antiidiotipicheskii otvet na vvedenie inaktivirovannogo ili zhivogo virusa grippa v éksperimente.

ABSTRACT

The injection of inactivated and live influenza virus into rabbits induces the formation of anti-idiotypic antibodies, appearing after anti-influenza hemagglutinins, in the blood. The presence of immune complexes antibody--anti-idiotypic antibody in the blood of the animals has been established. The booster immunization of the animals with influenza virus antigens produces a rise in the levels of both idiotypic and anti-idiotypic antibodies. The injection of autologous anti-idiotypic globulin into the primed animals ensures the induction of idiotypic and anti-idiotypic revaccinal reactions.