Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma: A preliminary study.
Med Oral Patol Oral Cir Bucal
; 13(2): E110-3, 2008 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-18223526
The aim of this study was to analyze proliferative verrucous leukoplakia (PVL) and oral squamous cell carcinoma (OSCC) for the possible presence of Epstein-Barr virus (EBV). We studied three groups: Sub-Group 1 was composed of 10 patients with PVL, (6 of whom had developed OSCC); Sub-Group 2 comprised 5 patients with OSCC but no preceding PVL; and Sub-Group 3 were 5 controls with clinically normal oral mucosa. Oral biopsies from all cases were examined for Epstein-Barr virus (EBV) by nested PCR. EBV was detected in 60% of Sub-Group 1 patients (PVL ) and in 40% of Sub-Group 2 (OSCC), but in 0% of Sub-Group 3 (controls).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucoplasia Oral
/
Neoplasias Bucais
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Carcinoma de Células Escamosas
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Herpesvirus Humano 4
Limite:
Adolescent
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Adult
/
Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Med Oral Patol Oral Cir Bucal
Ano de publicação:
2008
Tipo de documento:
Article