Peripheral administration of kisspeptin-10 increases plasma concentrations of GH as well as LH in prepubertal Holstein heifers.
J Endocrinol
; 196(2): 331-4, 2008 Feb.
Article
em En
| MEDLINE
| ID: mdl-18252956
ABSTRACT
This study was conducted to estimate the effects of kisspeptin-10 on blood concentrations of LH and GH in prepubertal dairy heifers. Heifers received a single injection of 1 mg kisspeptin-10 (n=5) or saline (n=5) intravenously, and serial blood samples were collected at 15-min intervals to analyze the response curves of both LH and GH after injection. Peak-shaped responses were observed for concentrations of LH and GH, and the peaks were observed at 27+/-3 and 75+/-9 min, respectively, after injection, only in heifers injected with kisspeptin-10. These data suggest various possible important links among kisspeptin, the reproductive axis, and also the somatotropic axis in prepubertal Holstein heifers.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligopeptídeos
/
Envelhecimento
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Hormônio do Crescimento
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Hormônio Luteinizante
Limite:
Animals
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Female
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Humans
Idioma:
En
Revista:
J Endocrinol
Ano de publicação:
2008
Tipo de documento:
Article