Long-term survival with stage IV poorly differentiated pancreatic adenocarcinoma.
HPB (Oxford)
; 6(2): 123-5, 2004.
Article
em En
| MEDLINE
| ID: mdl-18333063
ABSTRACT
BACKGROUND:
Metastatic poorly differentiated adenocarcinoma of the pancreas has a poor outcome despite the use of various chemotherapy regimes. CASE OUTLINE A 57-year-old woman presented with a 3-month history of generalised abdominal pain associated with weight loss. Computed tomography (CT) showed a large tumour in the head and body of pancreas, and needle biopsy confirmed a poorly differentiated adenocarcinoma. Laparoscopy revealed liver metastases in both lobes, again histologically shown to be poorly differentiated adenocarcinoma. Six cycles of cisplatin, epirubicin and infusional 5-fluorouracil were given. Five years later the patient remains completely well. Repeat CT scans show a complete radiological response.DISCUSSION:
Previous studies using numerous chemotherapy regimes have not significantly altered the outcome of pancreatic cancer. To the best of our knowledge this is the longest surviving case of a patient with advanced metastatic adenocarcinoma (stage IV) of the pancreas treated with chemotherapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
HPB (Oxford)
Ano de publicação:
2004
Tipo de documento:
Article