Synthesis of UDP-glucose derivatives modified at the 3-OH as potential chain terminators of beta-glucan biosynthesis.
Carbohydr Res
; 343(6): 1012-22, 2008 May 05.
Article
em En
| MEDLINE
| ID: mdl-18336802
ABSTRACT
A series of UDP-D-glucose derivatives and precursors that have been modified at C-3 were synthesised from D-glucose as potential chain terminators of beta-glucan biosynthesis. None of the UDP-derivatives or the precursors tested displayed significant anti-fungal activity in a series of germination assays on the dermatophyte Trichophyton rubrum.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trichophyton
/
Uridina Difosfato Glucose
/
Beta-Glucanas
/
Antifúngicos
Idioma:
En
Revista:
Carbohydr Res
Ano de publicação:
2008
Tipo de documento:
Article