Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate.
Turk Neurosurg
; 18(1): 85-8, 2008 Jan.
Article
em En
| MEDLINE
| ID: mdl-18382986
ABSTRACT
Congenital protein S deficiency is associated with an increased risk of venous thrombosis. A14-year-old boy presented with epileptic seizures and thrombosis of the superior sagittal sinus and frontal hemorrhagic venous infarction after ingestion of 50 mg of dimenhydrinate, an antiemetic drug. The patient was found to be heterozygous for the factor V Leiden mutation and had a functional protein S deficiency. He recovered completely within a month after conservative treatment. Dimenhydrinate may have disrupted a subclinical pre-existing condition in this case.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infarto Cerebral
/
Deficiência de Proteína S
/
Trombose do Seio Sagital
/
Dimenidrinato
/
Epilepsia
/
Antieméticos
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Turk Neurosurg
Ano de publicação:
2008
Tipo de documento:
Article