A genetic decomposition of the association between parasomnias and dyssomnias in 8-year-old twins.
Arch Pediatr Adolesc Med
; 162(4): 299-304, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-18391137
ABSTRACT
OBJECTIVE:
To estimate genetic and environmental influences on parasomnias and dyssomnias and their association in 8-year-olds.DESIGN:
Parents of twins completed the Children's Sleep Habits Questionnaire.SETTING:
Families were primarily tested at the Institute of Psychiatry, London, England.PARTICIPANTS:
A total of 300 pairs of 8-year-old twins and their parents participated in the study. MAIN OUTCOMEMEASURES:
Sleep difficulties in children.RESULTS:
Individual differences in parasomnias and dyssomnias were largely explained by genes (accounting for 50% and 71% of the variances, respectively). The rest of the variances were mainly due to nonshared environmental influences. A moderate association was found between parasomnias and dyssomnias (r = 0.42), which was mainly accounted for by genetic influences (87%). The genetic correlation between parasomnias and dyssomnias was moderate (r = 0.61). In contrast, the nonshared environmental correlation was small (r = 0.10).CONCLUSIONS:
The decomposition of the association between parasomnias and dyssomnias suggests that there may be different manifestations of shared underlying genetic risks for sleep problems partly dependent on nonshared environmental influence.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gêmeos
/
Gêmeos Dizigóticos
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Gêmeos Monozigóticos
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Dissonias
/
Parassonias
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Arch Pediatr Adolesc Med
Ano de publicação:
2008
Tipo de documento:
Article