Leucocyte adhesion defect-1.
Indian Pediatr
; 45(6): 507-9, 2008 Jun.
Article
em En
| MEDLINE
| ID: mdl-18599942
ABSTRACT
Leucocyte adhesion defect (LAD) is an inherited disorder of phagocytic function. It is characterized by inability of the leucocytes, in particular neutrophilis to migrate from the blood stream towards sites of inflammation. LAD -1 is characterized by the absence of b 2 integrins (CD 11 / CD18) on leucocytes. This disorder is characterized by delayed separation of the umbilical cord, recurrent severe infections, periodontitis, and delayed wound healing. We report an infant where the diagnosis was confirmed by flow cytometry.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome da Aderência Leucocítica Deficitária
Limite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Indian Pediatr
Ano de publicação:
2008
Tipo de documento:
Article