APOE epsilon4 is associated with postictal confusion in patients with medically refractory temporal lobe epilepsy.
Epilepsy Res
; 81(2-3): 220-4, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-18672349
ABSTRACT
This study examined the relationship between the APOE epsilon4 allele and postictal confusion in patients with medically intractable temporal lobe epilepsy (TLE). Patients with at least one epsilon4 allele (n=22) were three times more likely to exhibit postictal confusion (68%) than the 63 patients without epsilon4 (43%). These preliminary results demonstrate that APOE epsilon4 is associated with an increased risk of postictal confusion in patients with medically intractable TLE, suggesting possible dysfunction in neuronal recovery mechanisms.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Confusão
/
Epilepsia do Lobo Temporal
/
Apolipoproteína E4
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Epilepsy Res
Ano de publicação:
2008
Tipo de documento:
Article