[Chromosome 17 abnormalities in medulloblastomas and their prognostic value].

Korshunov, A G; Sycheva, R V; Gorelyshev, S K; Ozerov, S S; Golanov, A V

Korshunov, A G; Sycheva, R V; Gorelyshev, S K; Ozerov, S S; Golanov, A V.

Zh Vopr Neirokhir Im N N Burdenko ; (2): 3-5; discussion 5, 2008.

Article em Ru | MEDLINE | ID: mdl-18724421

ABSTRACT

ABSTRACT

The cytogenetic profile of chromosome 17 was studied in 180 medlloblastomas by the interphasic FISH technique, which revealed the high incidence of this aberration and its association with the poor clinical course of the disease. The interphasic cytogenetic analysis of chromosome 17 abnormalities in medulloblastoma biopsy specimens may be recommended for its inclusion into a complex of laboratory diagnostic methods used in the examination of these tumors.

Assuntos

Neoplasias Cerebelares/genética; Aberrações Cromossômicas; Cromossomos Humanos Par 17/genética; Meduloblastoma/genética; Adolescente; Adulto; Neoplasias Cerebelares/epidemiologia; Neoplasias Cerebelares/terapia; Feminino; Humanos; Hibridização in Situ Fluorescente; Estimativa de Kaplan-Meier; Masculino; Meduloblastoma/epidemiologia; Meduloblastoma/terapia; Valor Preditivo dos Testes

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 17 / Neoplasias Cerebelares / Aberrações Cromossômicas / Meduloblastoma Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: Ru Revista: Zh Vopr Neirokhir Im N N Burdenko Ano de publicação: 2008 Tipo de documento: Article

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