[Effects of Rhodiola rosea on body weight and intake of sucrose and water in depressive rats induced by chronic mild stress].
Zhong Xi Yi Jie He Xue Bao
; 6(9): 952-5, 2008 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-18782541
ABSTRACT
OBJECTIVE:
To explore the effects of Rhodiola rosea on the body weight and the intake of sucrose and water in depressive rats induced by chronic mild stress.dzMETHODS:
A total of 70 male SD rats were divided into seven groups, including normal control group (treated with 0.5% sodium carboxymethycellulose), untreated group, negative control group (treated with 0.5% sodium carboxymethycellulose), positive control group (treated with fluoxetine), low-, medium- and high-dose Rhodiola rosea group (treated with 1.5, 3, 6 g/kg Rhodiola rosea respectively). Except for rats in normal control group, the other sixty rats endured chronic stress for 4 weeks to establish the depression model. After that, rats were administered Rhodiola rosea for 3 weeks. During the whole experiment, the body weight, and sucrose intake, tap water intake of all rats were examined once a week.RESULTS:
After the termination of the stress regime, compared with the normal control group, the body weight and 1% sucrose intake in depressive rats were decreased. After 3-week Rhodiola rosea treatment, the body weight and 1% sucrose intake increased in rats of the low-dose Rhodiola rosea group and recovered to the level of the normal control group.CONCLUSION:
Low-dose Rhodiola rosea can increase the body weight and sucrose intake of depressive rats, making them recover to normal status.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peso Corporal
/
Rhodiola
/
Depressão
/
Ingestão de Líquidos
/
Fitoterapia
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Revista:
Zhong Xi Yi Jie He Xue Bao
Ano de publicação:
2008
Tipo de documento:
Article