[Characterization of rabies virus phosphoprotein in high prevalence provinces of China].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
; 22(3): 165-7, 2008 Jun.
Article
em Zh
| MEDLINE
| ID: mdl-19031691
ABSTRACT
OBJECTIVE:
Characterization of rabies virus phosphoprotein through analyzation of genetic variations about rabies virus phosphoproteins in high-incidence regions in China.METHODS:
The nucleotide sequence of the P gene of Guangxi, Guizhou and Hunan provinces positive sample's were sequenced, and the P region's similarity and phylogenetic analyses were completed by using softer wares.RESULTS:
The similarity of P region's nucleotide sequence is 82.1%-100%, while, the similarity of amino acid sequence is 87.5%-100%. A little variation in phosphoprotein cannot influence its biological functions.CONCLUSION:
All rabies viruses isolated from Guangxi, Guizhou and Hunan provinces belong to genotype 1 and share same phylogenesis and same genome characteristic; Virus distribution presents unique Characterization; Some virus isolates from Hunan province and Thailand may come from the same virus.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Fosfoproteínas
/
Raiva
/
Vírus da Raiva
/
Proteínas Estruturais Virais
/
Doenças do Cão
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Animals
/
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
Ano de publicação:
2008
Tipo de documento:
Article