Coarse-grained modeling of interactions of lipid bilayers with supports.
J Chem Phys
; 129(17): 175102, 2008 Nov 07.
Article
em En
| MEDLINE
| ID: mdl-19045374
ABSTRACT
We characterize the differences between supported and unsupported lipid bilayer membranes using a mesoscopic simulation model and a simple particle-based realization for a flat support on to which the lipids are adsorbed. We show that the nanometer roughness of the support affects membrane binding strength very little. We then compare the lipid distributions and pressure profiles of free and supported membranes. The surface localization of the proximal leaflet breaks the symmetry seen in a free bilayer, and we quantify the entropic penalty for binding and the increased lateral compression modulus.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bicamadas Lipídicas
/
Modelos Químicos
Idioma:
En
Revista:
J Chem Phys
Ano de publicação:
2008
Tipo de documento:
Article