Location, location, location: B-cell differentiation in the gut lamina propria.
Mucosal Immunol
; 1(1): 8-10, 2008 Jan.
Article
em En
| MEDLINE
| ID: mdl-19079155
ABSTRACT
The intestinal immune system includes an immunoglobulin (Ig)A-inductive site represented by Peyer's patches (PPs) and an IgA effector site represented by the lamina propria (LP). This canonical map of intestinal IgA production has been blurred recently by studies showing the presence of active IgA class switching in the LP. Here we discuss the functional implications and controversial nature of these findings.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nódulos Linfáticos Agregados
/
Plasmócitos
/
Imunoglobulina A
/
Linfócitos B
/
Diferenciação Celular
/
Imunidade nas Mucosas
/
Células Precursoras de Linfócitos B
/
Tecido Linfoide
/
Formação de Anticorpos
/
Mucosa
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Mucosal Immunol
Ano de publicação:
2008
Tipo de documento:
Article