The association between arsenic and children's intelligence: a meta-analysis.
Biol Trace Elem Res
; 129(1-3): 88-93, 2009.
Article
em En
| MEDLINE
| ID: mdl-19107329
ABSTRACT
This present study was undertaken to investigate whether arsenic exposure increases the risk of children's low intelligence quotient (IQ) in China. MEDLINE, SCI, CNKI, and CBM search were organized for all documents published, in English and Chinese, between 1988 and 2008 using the following keywords arsenic, intelligence, and IQ. As a result, four cross-sectional studies that assessed the development of low IQ in children who had been exposed to arsenic earlier in their life were included in this study. The summary weighted mean difference of IQ was calculated in this meta-analyses, when arsenicosis areas or slight arsenicosis areas were compared with non-arsenicosis areas; it is -6.85 (95% confidence interval [CI] = -8.30 to -5.41; p < 0.01, using a fixed effect model) and -6.54 (95%CI = -8.93 to -4.15; p < 0.01, using a random effect model), which means that children who live in an arsenicosis area or a slight arsenicosis area have lower IQ than those who live in a non-arsenicosis area, and there may be a strong association between arsenic and children's intelligence.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arsênio
/
Inteligência
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Biol Trace Elem Res
Ano de publicação:
2009
Tipo de documento:
Article