Treatment of Evans' syndrome with human intravenous immunoglobulin and leflunomide in a diabetic dog.
J Am Anim Hosp Assoc
; 45(3): 147-50, 2009.
Article
em En
| MEDLINE
| ID: mdl-19411652
ABSTRACT
An 11-year-old, spayed female miniature schnauzer with diabetes mellitus was presumptively diagnosed with Evans' syndrome (ES). Because of the potential adverse effects of immunosuppressive doses of glucocorticoids in a diabetic dog, a single infusion of human intravenous immunoglobulin and oral leflunomide were used as first-line immunomodulatory therapy, after informed owner consent was received. This treatment resulted in complete remission of the ES, and leflunomide was discontinued after 10 months of therapy. Over a 19-month follow-up, the dog did not relapse and has remained a well-regulated diabetic.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Púrpura Trombocitopênica Idiopática
/
Imunoglobulinas Intravenosas
/
Doenças do Cão
/
Fatores Imunológicos
/
Anemia Hemolítica Autoimune
/
Isoxazóis
Limite:
Animals
Idioma:
En
Revista:
J Am Anim Hosp Assoc
Ano de publicação:
2009
Tipo de documento:
Article