[Merkel cell carcinoma: an uncommon neuroendocrine cancer]. / Il carcinoma a cellule di Merkel: una rara neoplasia neuroendocrina.
G Chir
; 30(5): 226-9, 2009 May.
Article
em It
| MEDLINE
| ID: mdl-19505415
ABSTRACT
Merkel cell carcinoma (MCC), firstly described by Torker in 1972, is an uncommon and aggressive neuroendocrine cancer of the skin. MCC tends to recur and precociously spread to lymph nodes. Five-year survival rate is between 35 and 75%. In literature there are not univocal criteria regarding the diagnosis and therapy of MCC, probably due to its rarity. Surgery plays an important role in the therapeutic strategy of this cancer. Surgical excision must be wide and guarantee at least 2-3 cm of free tumor margins. Sentinel lymph node biopsy is useful to identify those patients in which extensive lymph node dissection and/or adjuvant therapies (radio- and/or chemotherapy) are advisable. We hereby report a case of MCC of the left arm in a 48 year-old male. A wide excision was performed with sentinel lymph node biopsy that did not show any metastasis. Adjuvant radio therapy was administered. The patient was healthy at one year follow-up.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Braço
/
Neoplasias Cutâneas
/
Carcinoma de Célula de Merkel
/
Biópsia de Linfonodo Sentinela
Tipo de estudo:
Prognostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
It
Revista:
G Chir
Ano de publicação:
2009
Tipo de documento:
Article