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Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice.
Awasthy, Disha; Gaonkar, Sheshagiri; Shandil, R K; Yadav, Reena; Bharath, Sowmya; Marcel, Nimi; Subbulakshmi, Venkita; Sharma, Umender.
Afiliação
  • Awasthy D; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Gaonkar S; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Shandil RK; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Yadav R; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Bharath S; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Marcel N; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Subbulakshmi V; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
  • Sharma U; AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India.
Microbiology (Reading) ; 155(Pt 9): 2978-2987, 2009 Sep.
Article em En | MEDLINE | ID: mdl-19542000
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Base de dados: MEDLINE Assunto principal: Acetolactato Sintase / Tuberculose Pulmonar / Aminoácidos de Cadeia Ramificada / Mycobacterium tuberculosis Limite: Animals Idioma: En Revista: Microbiology (Reading) Ano de publicação: 2009 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Base de dados: MEDLINE Assunto principal: Acetolactato Sintase / Tuberculose Pulmonar / Aminoácidos de Cadeia Ramificada / Mycobacterium tuberculosis Limite: Animals Idioma: En Revista: Microbiology (Reading) Ano de publicação: 2009 Tipo de documento: Article