Complementary chemoenzymatic routes to both enantiomers of febrifugine.
Org Biomol Chem
; 7(14): 2976-80, 2009 Jul 21.
Article
em En
| MEDLINE
| ID: mdl-19582308
ABSTRACT
Two complementary strategies for the synthesis of febrifugine are detailed based on previously developed chemoenzymatic approaches to the 3-hydroxypiperidine skeleton. The introduction of the quinazolone-containing side chain in both strategies was based on an N-acyliminium ion-mediated coupling reaction.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piperidinas
/
Quinazolinas
Idioma:
En
Revista:
Org Biomol Chem
Ano de publicação:
2009
Tipo de documento:
Article