[Successful treatment of treatment-resistant opioid-induced constipation in a patient with incomplete paraplegia with methylnaltrexone]. / Behandlung einer therapieresistenten, opioidbedingten Obstipation bei inkomplettem Querschnittssyndrom mit Methylnaltrexon.
Schmerz
; 23(5): 523-4, 2009 Oct.
Article
em De
| MEDLINE
| ID: mdl-19585156
ABSTRACT
We observed a patient with incomplete, cervical paraplegia and opioid-induced constipation who developed a resistance to laxatives after 15 years of treatment. The constipation-induced reduction in the patient's quality of life was improved using 12 mg methylnaltrexone, a peripheral mu-opioid receptor antagonist, administered subcutaneously twice a week.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Paraplegia
/
Constipação Intestinal
/
Naltrexona
/
Antagonistas de Entorpecentes
/
Entorpecentes
Aspecto:
Patient_preference
Limite:
Aged
/
Humans
/
Male
Idioma:
De
Revista:
Schmerz
Ano de publicação:
2009
Tipo de documento:
Article