Temporal fossa hemangiopericytoma: a case series.
Otol Neurotol
; 30(7): 985-9, 2009 Oct.
Article
em En
| MEDLINE
| ID: mdl-19707170
ABSTRACT
OBJECTIVE:
Review clinical experience with temporal fossa hemangiopericytomas (HPCs). STUDYDESIGN:
Retrospective case series review.SETTING:
Tertiary referral center. PATIENTS Intracranial HPCs within the temporal fossa.INTERVENTIONS:
Craniotomy for either subtotal or gross total tumor excision. MAIN OUTCOMEMEASURES:
Determination of clinical outcome (alive with no evidence of disease, alive with disease, and died of disease).RESULTS:
Five cases of HPC involving the temporal fossa were treated at our tertiary referral center for the period from 1995 to 2008. All but 1 patient were men. The age of presentation ranged from 31 to 62 years, and duration of follow-up ranged from 8 to 153 months. Clinical presentation was protean; headache was the most common symptom. Gross total tumor excision was achieved in 2 patients, whereas subtotal tumor excision was achieved in 3 patients. Reasons for subtotal resection included excessive intraoperative blood loss and inextricable tumor. Histologically, all tumors were composed of tightly packed, randomly oriented (jumbled-up) tumor cells with little intervening collagen. CD34 staining mostly highlighted the vascular background. One patient died of disease, 2 patients were alive with disease, and 2 patients had no evidence of disease.CONCLUSION:
Management of temporal fossa HPC is challenging because clinical presentation is often late, and extent of tumor excision is constrained by vital structures in the cranial base and intracranial contents. A multidisciplinary approach with neurosurgery and neurotology undertaken to achieve the most complete tumor resection possible, whereas minimizing morbidity are likely to confer a longer period of symptom-free survival and improves curability of these difficult lesions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cranianas
/
Hemangiopericitoma
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Otol Neurotol
Ano de publicação:
2009
Tipo de documento:
Article