Signs of striatal dopamine transporter density increase in association with improvement of tardive dyskinesia in a patient with schizophrenia, as demonstrated by a DAT scan.
Eur Neuropsychopharmacol
; 20(2): 132-6, 2010 Feb.
Article
em En
| MEDLINE
| ID: mdl-19740630
ABSTRACT
The imaging of the dopamine transporter could demonstrate the implication of dopaminergic pathway in the appearance of tardive dyskinesia. We report a case with psychotic and tardive dyskinesia symptoms. A DAT scan showed decreased dopamine transporter uptake in the area of brain's basal gaglia. A trial with quetiapine improved both psychotic and TD symptoms while a second DAT scan showed improvement status. We conclude that increased dopamine transporter uptake seemed to associate with the improvement of TD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Tomografia Computadorizada de Emissão de Fóton Único
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Corpo Estriado
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Discinesia Induzida por Medicamentos
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Proteínas da Membrana Plasmática de Transporte de Dopamina
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Eur Neuropsychopharmacol
Ano de publicação:
2010
Tipo de documento:
Article