Behaviour of ceftazidime towards beta-lactamases.
J Antimicrob Chemother
; 8 Suppl B: 141-6, 1981 Sep.
Article
em En
| MEDLINE
| ID: mdl-19810176
ABSTRACT
from Escherichia coli, Enterobacter cloacae, Proteus morganii and Pseudomonas aeruginosa, but the geometric mean of the inhibition constant Ki used to measure this interaction was 120 and almost 700 times higher with ceftazidime than with cefotaxime and cefuroxime, respectively. Two other beta-lactamases isolated from Pr. vulgaris and Klebsiella oxytoca also showed little or no interaction with ceftazidime. A complementary microbiological technique, the "double-disc" technique, indicated that ceftazidime was more stable than cefotaxime to all beta-lactamases tested. Moxalactam, however, appeared to have slightly greater stability.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Beta-Lactamases
/
Ceftazidima
/
Antibacterianos
Idioma:
En
Revista:
J Antimicrob Chemother
Ano de publicação:
1981
Tipo de documento:
Article