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Acute stroke patients with high BMI are less likely to have severe disability at initial presentation.
Choo, W S; Foo, S; Tan, E; Thayaparan, F S T; Chung, Y Y; Raman, S; Shaariah, W; Chin, S P.
Afiliação
  • Choo WS; Department of Medicine, Hospital Tuanku Ja'afar, Seremban. waisun76@yahoo.com
Med J Malaysia ; 64(1): 34-6, 2009 Mar.
Article em En | MEDLINE | ID: mdl-19852318
ABSTRACT
This is a prospective study to determine the severity of disability and prognosis of acute stroke patients related to their Body Mass index (BMI). A total of 79 consecutive CT-scan-proven acute stroke patients who were admitted to Hospital Tuanku Ja'afar, Seremban between November 2006 and April 2007 were recruited (malefemale 4930; mean age 62.7 years; ischemic stroke 70, intracerebral bleed 9). The patients were divided according to BMI less than 25 (Group A) and equal or greater than 25 (Group B). Severity of disability was measured between 24-48 hours by modified Rankin's score. Patients were followed up after one month. Thirty-seven patients had severe disability (Rankin Score 5). Twenty-nine patients had adverse outcomes including 11 deaths and 18 rehospitalizations or prolonged hospital/nursing home stay. 34.3% of Group B had severe disability compared to 56.8% of Group A (chi2 P = 0.046). Conversely 42.9% of Group B had adverse events at one month compared to 31.8% of Group A (chi2 P = 0.312). There were no statistical differences between high- and low-BMI groups for gender ratio, smoking, hypertension, diabetes, prior cardiovascular disease, mean age, mean lipid profile and blood pressure. When comparing patients with Rankin Score 1-4 versus 5, age and BMI were statistically significant between the two groups. By multivariate analysis only age is independent predictor for severe disability (P < 0.05). The results of this pilot study should be confirmed in larger prospective multicentre trial.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Pessoas com Deficiência / Acidente Vascular Cerebral Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Med J Malaysia Ano de publicação: 2009 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Pessoas com Deficiência / Acidente Vascular Cerebral Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Med J Malaysia Ano de publicação: 2009 Tipo de documento: Article