2-aryl-3-(1H-azol-1-yl)-1H-indole derivatives: a new class of antimycobacterial compounds - conventional heating in comparison with MW-assisted synthesis.
Arch Pharm (Weinheim)
; 342(12): 716-22, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19921681
ABSTRACT
2-Aryl-3-(1H-imidazol-1-yl and 1H-1,2,4-triazol-1-yl)-1H-indole derivatives were synthesized and tested for their in-vitro antifungal and antimycobacterial activities. These indole derivatives were devoid of antifungal activity against the tested strains of Candida spp. Yet, they exhibited an interesting antitubercular activity against Mycobacterium tuberculosis reference strain H(37)Rv.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Candida
/
Química Farmacêutica
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Indóis
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Antibacterianos
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Mycobacterium tuberculosis
/
Antifúngicos
Idioma:
En
Revista:
Arch Pharm (Weinheim)
Ano de publicação:
2009
Tipo de documento:
Article