Fertility after uterine artery embolization: investigation using a sheep model.
Reprod Sci
; 17(4): 350-7, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-19949190
ABSTRACT
OBJECTIVE:
To investigate the influence of uterine artery embolization (UAE) on fertility after bilateral UAE with either tris-acryl gelatin microspheres (TAGM) or gelatin particles (GP). MATERIALS ANDMETHODS:
Six ewes that underwent UAE with TAGM, 6 ewes that underwent UAE with GP, and 6 control ewes were compared. After hormonal synchronization of the menstrual cycle, artificial insemination (AI) was performed. When pregnancy did not result, ewes were naturally inseminated.RESULTS:
After AI, progesterone concentrations in blood increased and were maintained at >1.0 ng/mL in 9 ewes (3 per group). Three ewes became pregnant after AI. The abortion rate was higher in the UAE group. The remaining 15 sheep were naturally inseminated, with 14 delivering 15 lambs. Mean period of term gestation in UAE group ewes was 155.7 versus 158.6 days in control group ewes. Lambs' body weight, body length, and withers height after birth did not differ between those from UAE group and control group. Lambs from ewes embolized with GP tended to be smaller and had lower body weight than those from other groups.CONCLUSION:
Uterine artery embolization influenced reproductive ability in sheep and UAE with GP could lead to intrauterine growth retardation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Embolização da Artéria Uterina
/
Retardo do Crescimento Fetal
/
Infertilidade Feminina
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Reprod Sci
Ano de publicação:
2010
Tipo de documento:
Article