Virulence of ureaplasmal urease for mice.
Infect Immun
; 59(3): 1170-1, 1991 Mar.
Article
em En
| MEDLINE
| ID: mdl-1997418
ABSTRACT
Ureaplasmas killed mice within 5 min after intravenous injection. The 50% lethal dose of whole ureaplasmal organisms was 32 micrograms per mouse, a value also found for crystalline jackbean urease. The reaction was specific to urease, since protection was afforded by intraperitoneal injection of 200 micrograms of flurofamide, a potent urease inhibitor. The finding that a similar lethal effect was produced by injection of 200 mumol of NH4+ indicates that the toxicity of urease is mediated by ammonium ions or free ammonia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ureaplasma
/
Urease
Limite:
Animals
Idioma:
En
Revista:
Infect Immun
Ano de publicação:
1991
Tipo de documento:
Article