[Seroepidemical study of Coxsackievirus A 16, in four provinces, China, 2005].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
; 23(2): 103-5, 2009 Apr.
Article
em Zh
| MEDLINE
| ID: mdl-20104748
ABSTRACT
OBJECTIVE:
To study the situation of 1- 5-years-old children's antibody against Coxsackievirus A group 16 strain (CVA16) in Guangdong, Heilongjiang,Yunnan Province and Xinjiang Uygur Autonomous Regions, China, 2005, it can offer scientific evidences for preventing and controlling CVA16 causative hand-food and mouth disease.METHODS:
Using microneutrilization test, to study 503 serum samples randomly selected from sera collected in 2005.RESULTS:
Positive rate of anti-CVA16 antibody were 41.90%, 9.40%, 40.00% and 34.40% in Guangdong, Heilongjiang,Yunnan and Xinjiang, respectively. Antibody titer was relative low (average, 1 6.1) and there was no statistical difference of geometry mean of antibody titer (GMT) among Guangdong, Heilongjiang, Yunnan (F = 0.97, 0.40, 1.06, respectively; P > 0.05), while there had statistical difference of GMT between Heilongjiang and other three regions( F = 10.61, P < 0.00).CONCLUSIONS:
There had probably existed local epidemic in some regions of Guangdong, Heilongjiang, Yunnan Province and Xinjiang Uygur Autonomous Regions, China, 2005 or even before, but the area and degree of transmission and epidemic had difference. Children aged from 1- 5-years-old were relatively susceptible population of CVA16 infection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Enterovirus Humano A
/
Infecções por Enterovirus
Limite:
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
Ano de publicação:
2009
Tipo de documento:
Article