[Childhood bacterial meningitis trends in Japan from 2007 to 2008].
Kansenshogaku Zasshi
; 84(1): 33-41, 2010 Jan.
Article
em Ja
| MEDLINE
| ID: mdl-20170012
ABSTRACT
We surveyed pediatrics bacterial meningitis epidemiology from January 2007 to December 2008 in Japan, with the following results:
Cases numbered 287-160 male and 127 female-equivalent to 1.54-1.62 of 1,000 pediatric hospitalization per year. Children under 1-year-old accounted for the highest number of cases, which decreased with increasing age. Haemophilus influenzae was the most common cause of infection, followed by Streptococcus pneumoniae, group B streptococcus (GBS), and Escherichia coli. GBS and E. coli were major pathogens in children under 4 months of age, while H. influenzae and S. pneumoniae mainly accounted for those over 4 months of age. Susceptibility tests showed that 51% of H. influenzae isolates and 56.5% of S. pneumoniae isolates in 2008 were drug-resistant. Ampicillin combined with cephem antibiotics effective against GBS, E. coli, and Listeria, were mainly used to initially treat those under 4 months of age. In those over 4 months of age, carbapenem antibiotics are effective against PRSP and cephem antibiotics against H. influenza.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Meningites Bacterianas
Limite:
Female
/
Humans
/
Infant
/
Male
/
Newborn
País/Região como assunto:
Asia
Idioma:
Ja
Revista:
Kansenshogaku Zasshi
Ano de publicação:
2010
Tipo de documento:
Article