[MRI scan of striatum volume in healthy adults].
Zhejiang Da Xue Xue Bao Yi Xue Ban
; 39(2): 130-5, 2010 03.
Article
em Zh
| MEDLINE
| ID: mdl-20387239
ABSTRACT
OBJECTIVE:
To examine the age, sex, and hemispheric differences in volume of the striatum by MRI in healthy adults.METHODS:
The volumes of the bilateral caudate nucleus and putamen were measured on MR images in 100 healthy right-handed adults (18-70 y).RESULTS:
The volume of bilateral caudate nucleus and putamen in healthy adults was (8.42 +/-0.88) cm(3) and (8.90 +/-0.89) cm(3), which were decreased with aging (for caudate nucleus r=-0.727, P<0.001; for putamen r=-0.709, P<0.001). The average annual shrinkage rate was 0.52 % in the caudate nucleus and 0.50 % in the putamen. There were no gender differences in the volume of the striatum, however, the age-related shrinkage of the striatum was more evident in men than that in women. The volume of the left caudate nucleus (t=4.43, P<0.001) and the putamen (t=4.88, P<0.001) was greater than that of its right counterpart.CONCLUSION:
Bilateral age-related shrinkage of the striatum is found in healthy adults, which is more evident in men than that in women. In both sexes, significant leftward asymmetry in volume of the caudate nucleus and the putamen is found.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Corpo Estriado
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Zhejiang Da Xue Xue Bao Yi Xue Ban
Ano de publicação:
2010
Tipo de documento:
Article