Cytotoxic triterpenoids from Ganoderma lucidum.
Phytochemistry
; 71(13): 1579-85, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20615519
ABSTRACT
A systematic study of the metabolites in Ganoderma lucidum led to isolation of 43 triterpenoids, six of them (1-6) are hitherto unknown. The structures of the latter were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. All of the compounds were assayed for their inhibitory activities against human HeLa cervical cancer cell lines. Some compounds exhibit significant cytotoxicity, and their structure-activity relationships are discussed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Reishi
Limite:
Humans
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2010
Tipo de documento:
Article