¹8F-FDG and ¹¹C-MET positron emission tomography findings of cutaneous mast cell tumor in a dog.
J Vet Med Sci
; 73(3): 355-9, 2011 Mar.
Article
em En
| MEDLINE
| ID: mdl-20962463
ABSTRACT
A 12-year-old intact male Maltese dog presented with an inguinal mass. Histopathology revealed a grade III mast cell tumor. Computed tomography demonstrated pulmonary and inguinal nodules and masses. Chemotherapy was performed using a vinblastine/prednisone protocol, and the inguinal mass disappeared 5 weeks later. Use of 2-deoxy-2-[¹8F]fluoro-D-glucose (¹8F-FDG) and (L)-[methyl- ¹¹C]methionine (¹¹C-MET)-positron emission tomography (PET) demonstrated hypermetabolic areas in the lungs and inguinal region one week after initial chemotherapy. The standardized uptake values of ¹8F-FDG were not different between lung and inguinal lesions; however, the inguinal lesion had a higher ¹¹C-MET standardized uptake value than the lung lesions. The hypermetabolic area was still visible on the second ¹8F-FDG-PET scan despite the disappearance of the mass. This is the first report of ¹¹C-MET-PET findings associated with a cutaneous mast cell tumor in a dog.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Fluordesoxiglucose F18
/
Mastocitoma
/
Tomografia por Emissão de Pósitrons
/
Doenças do Cão
/
Metionina
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Vet Med Sci
Ano de publicação:
2011
Tipo de documento:
Article