[Vaccination against pneumococci and influenza. How good is the evidence?]. / Impfungen gegen Pneumokokken und Influenza. Wie groß ist die Evidenz?
Internist (Berl)
; 52(3): 265-76, 2011 Mar.
Article
em De
| MEDLINE
| ID: mdl-20978734
ABSTRACT
Diseases caused by pneumococci and influenza viruses can lead to severe complications in children, in older, chronically ill and immunosuppressed patients. In an aging population in western countries they present an important cause of morbidity and mortality. Additionally, antibiotic resistance may complicate a therapy. Consequently, the need of an effective vaccine is obvious. The 23-valent polysaccharide pneumococcal vaccine has been discussed critically. New meta-analyses do not show an efficacy in preventing invasive pneumococcal disease or death of all cause. However, a very recent study has shown a significant reduction of pneumonias and death due to pneumococcal disease in nursing-home residents. The 7-valent conjugated vaccine is more immunogenic and efficient in children and first studies demonstrate its efficacy in immunosuppressed persons. In Switzerland this latter vaccine is used in children, in Germany the 7-valent vaccine has been replaced by the 13-valent conjugated vaccine since December 2009. Influenza-vaccines are effective, while vaccines with an adjuvance seem more immunogenic, in particular in older persons. The 2010/2011 influenza vaccine has been adapted and includes the pandemic influenza H1N1 2009 strain. The influenza vaccine often does not provide protection against infection, however, it does provide good efficacy against severe complications related to influenza.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
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2_ODS3
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4_TD
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6_ODS3_enfermedades_notrasmisibles
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7_ODS3_muertes_prevenibles_nacidos_ninos
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Pneumocócica
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Vacinas contra Influenza
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Bacteriemia
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Medicina Baseada em Evidências
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Vacinas Pneumocócicas
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Influenza Humana
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Meningite Pneumocócica
Tipo de estudo:
Etiology_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Child
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Humans
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Middle aged
Idioma:
De
Revista:
Internist (Berl)
Ano de publicação:
2011
Tipo de documento:
Article