Selective estrogen receptor modulators as brain therapeutic agents.
J Mol Endocrinol
; 46(1): R1-9, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-21071476
ABSTRACT
Selective estrogen receptor modulators (SERMs), used for the treatment of breast cancer, osteoporosis, and menopausal symptoms, affect the nervous system. Some SERMs trigger neuroprotective mechanisms and reduce neural damage in different experimental models of neural trauma, brain inflammation, neurodegenerative diseases, cognitive impairment, and affective disorders. New SERMs with specific actions on neurons and glial cells may represent promising therapeutic tools for the brain.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Encefalopatias
/
Receptores de Estrogênio
/
Fármacos Neuroprotetores
/
Moduladores Seletivos de Receptor Estrogênico
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Mol Endocrinol
Ano de publicação:
2011
Tipo de documento:
Article