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Association between dietary fat content and outcomes in pediatric burn patients.
Lee, Jong O; Gauglitz, Gerd G; Herndon, David N; Hawkins, Hal K; Halder, Stefanie C; Jeschke, Marc G.
Afiliação
  • Lee JO; Shriners Hospitals for Children, University of Texas Medical Branch, Galveston, Texas, USA.
J Surg Res ; 166(1): e83-90, 2011 Mar.
Article em En | MEDLINE | ID: mdl-21109263
ABSTRACT

BACKGROUND:

The aim of the study was to compare a low fat/high-carbohydrate diet and a high-fat diet on clinical outcomes by a retrospective cohort study.

METHODS:

Nine hundred forty-four children with burns ≥ 40% of their total body surface area (TBSA) were divided into two groups patients receiving Vivonex T.E.N. (low-fat/high-carbohydrate diet; n = 518) and patients receiving milk (high-fat diet; n = 426). Patient demographics, caloric intake, length of hospital stay, and incidence of sepsis, mortality, hepatic steatosis, and organomegaly at autopsy were determined.

RESULTS:

Demographics and caloric intake were similar in both groups. Patients receiving Vivonex T.E.N. had shorter (intensive care unit) ICU stays (Vivonex T.E.N. 31 ± 2 d; milk 47 ± 2 d; P < 0.01), shorter ICU stay per % TBSA burn (Vivonex T.E.N. 0.51 ± 0.02 d/%; milk 0.77 ± 0.03 d/%; P < 0.01), lower incidence of sepsis (Vivonex T.E.N. 11%; milk 20%; P < 0.01), and lived significantly longer until death than those receiving milk (Vivonex T.E.N. 20 ± 3 d; milk 10 ± 2 d; P < 0.01). There was no difference in overall mortality between the two groups (Vivonex T.E.N.15% versus milk 13%; P < 0.9). Autopsies revealed decreased hepatic steatosis and decreased enlargement of kidney and spleen in patients receiving Vivonex T.E.N.

CONCLUSIONS:

The period with a low-fat/high-carbohydrate diet was associated with lower LOS, decreased incidence of organomegaly, infection, and hepatic steatosis post-burn compared with the period when a high-fat diet was used. These associations indicate the benefit of high carbohydrate/low fat nutrition; however, the findings in these time periods can also be likely due to the multifactorial effects of advances in burn care. We believe that these results have some relevance because high fat is associated with poorer outcomes compared with low fat.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queimaduras / Ingestão de Energia / Gorduras na Dieta Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Surg Res Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queimaduras / Ingestão de Energia / Gorduras na Dieta Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Surg Res Ano de publicação: 2011 Tipo de documento: Article