New sesquiterpene lactones from Glechoma hederacea L. and their cytotoxic effects on human cancer cell lines.
Planta Med
; 77(9): 955-7, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21243589
ABSTRACT
Three new sesquiterpene lactones, 1 α,10 ß-epoxy-4-hydroxy-glechoma-5-en-olide (1), 1 ß,10 α-epoxy-4,8-dihydroxy-glechoma-5-en-olide (2), and 1 ß,10 α;4 α,5 ß-diepoxy-8-methoxy-glechoman-8 α,12-olide (3), were isolated from the whole plant of Glechoma hederacea, together with four known sesquiterpene lactones. The structures of the three new sesquiterpene lactones were determined by spectroscopic evidence. Cytotoxic effects of the isolated compounds were examined against MDA-MB-231 (breast), HCT116 (colon), SW620 (colon), and DU145 (prostate) human cancer cell lines.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Extratos Vegetais
/
Lamiaceae
/
Lactonas
/
Antineoplásicos Fitogênicos
Limite:
Humans
Idioma:
En
Revista:
Planta Med
Ano de publicação:
2011
Tipo de documento:
Article