Consumptive hypothyroidism: a case report and review of the literature.
Ann Clin Biochem
; 48(Pt 2): 186-9, 2011 Mar.
Article
em En
| MEDLINE
| ID: mdl-21382982
ABSTRACT
Hepatic haemangioendothelioma is a rare vascular tumour in infants and may be associated with a unique form of thyroid function abnormalities. Hepatic haemangioendotheliomata is capable of producing an excess of the thyroid hormone inactivating enzyme, type 3 iodothyronine deiodinase. The increased enzyme activity leads to rapid degradation of thyroid hormones, resulting in frank hypothyroidism. We report a case of a three-month-old neonate with multiple hepatic haemangioendotheliomata and associated hypothyroidism. The patient required increasing doses of thyroid hormone.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemangioendotelioma
/
Hipotireoidismo
Limite:
Adult
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
En
Revista:
Ann Clin Biochem
Ano de publicação:
2011
Tipo de documento:
Article