Primary antiphospholipid syndrome presenting as renal vein thrombosis and membranous nephropathy.
Pediatr Nephrol
; 26(6): 979-85, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21431428
ABSTRACT
Antiphospholipid syndrome is a multisystem auto-immune disorder characterized by thrombotic events and the presence of circulating antiphospholipid antibodies. Large vessel involvement in the form of thrombosis/stenosis and thrombotic microangiopathy is a commonly described renal finding. However, non-thrombotic glomerulopathies are increasingly being recognized in patients with antiphospholipid syndrome. We report a rare occurrence of both renal vein thrombosis and membranous nephropathy in a previously healthy adolescent male. Investigations revealed persistently positive antiphospholipid antibodies in the absence of an underlying systemic autoimmune disorder or malignancy. Our patient responded favourably to anti-proteinuric therapy and anticoagulation with complete resolution of proteinuria and a nearly occlusive thrombus.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Veias Renais
/
Glomerulonefrite Membranosa
/
Síndrome Antifosfolipídica
/
Trombose Venosa
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Pediatr Nephrol
Ano de publicação:
2011
Tipo de documento:
Article