[Evaluation of magnetic resonance signal intensity in bone marrow after administration of super paramagnetic iron oxide (SPIO)].
Nihon Hoshasen Gijutsu Gakkai Zasshi
; 67(3): 212-20, 2011.
Article
em Ja
| MEDLINE
| ID: mdl-21471677
ABSTRACT
Super paramagnetic iron oxide (SPIO) is taken up in the bone marrow and lymph nodes, as well as by the liver. Focusing on the intervertebral disks, which are unaffected by contrast effects, we examined the relationship between magnetic resonance image (MRI) signal intensity after SPIO uptake in the vertebral body and intervertebral disks and investigated MRI signal intensity in bone marrow metastases and osteomyelitic (inflammatory) lesions after SPIO uptake by bone marrow. The lumbar spine was imaged in 5 healthy volunteers (age range, 26-48 years). A specified amount of SPIO was administered intravenously, and signal intensities before and after administration were measured. The signal intensity ratio with respect to the value before administration was calculated, and quantitative signal analysis was conducted. A similar investigation was performed in patients with bone metastasis and osteomyelitis. As a result of the metastasis, the signal intensity ratio showed a low value in comparison with normal marrow, and the osteomyelitis showed a high value in comparison with normal marrow. We report the usefulness of evaluations of changes in marrow signal intensity using SPIO in MRI.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medula Óssea
/
Imageamento por Ressonância Magnética
/
Compostos Férricos
/
Meios de Contraste
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
Ja
Revista:
Nihon Hoshasen Gijutsu Gakkai Zasshi
Ano de publicação:
2011
Tipo de documento:
Article