Perspectives on lymphangiogenesis and angiogenesis in cancer.
J Surg Oncol
; 103(6): 484-8, 2011 May 01.
Article
em En
| MEDLINE
| ID: mdl-21480240
ABSTRACT
Tumor-associated neovascularization allows tumor cells to express their critical growth advantage, whereas lymphatic invasion is crucial for the metastatic process. Various growth factors stimulate blood and lymphatic neovascularization and modulate vessel permeability in tumors. The first anti-angiogenic drugs are already in routine use, and new anti-vascular therapeutics are evaluated in clinical trials. Conversely, pro-lymphangiogenic therapy could be implemented to treat cancer survivors suffering from secondary lymphedema.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Linfangiogênese
/
Neoplasias
/
Neovascularização Patológica
Limite:
Humans
Idioma:
En
Revista:
J Surg Oncol
Ano de publicação:
2011
Tipo de documento:
Article