Correlations between C-reactive protein and metabolic syndrome or other associated diseases.

The aim of the paper is to present few aspects about the implication of the C-reactive protein (CRP) in the metabolic syndrome. High-sensitivity (hs) CRP is a marker of subclinical inflammation and it is a mediator of atherosclerotic disease. A recent study indicates a possible dose-effect relationship between waist circumference and hs-CRP levels. Elevated level of hs-CRP was associated with risk of developing metabolic syndrome (MS). However, cross-sectional studies have reported increased concentration of these inflammatory markers in both MS and over type 2 diabetes mellitus (DM) and prospective studies have found strong, graded relations between hs-CRP and incident diabetes. A growing number of large-scale studies are finding positive correlations of CRP with cardiovascular disease and these correlations are independent of smoking. The studies show that it is an association between chronic inflammation and depressive symptoms.