Morphologic and physiologic effects of thymoxamine on corneal endothelium and ciliary processes.
Lens Eye Toxic Res
; 7(3-4): 403-11, 1990.
Article
em En
| MEDLINE
| ID: mdl-2151607
ABSTRACT
Either 0.2 or 0.02% thymoxamine hydrochloride was perfused across the endothelium of isolated rabbit corneas in a specular microscope. Treated corneas did not swell, compared to controls, when perfused with 0.02% thymoxamine, but swelled at 34 microns/hr after 0.2% thymoxamine compared to 10 microns/hr of controls. Morphologically, 0.2% thymoxamine caused many intracellular vacuoles, with far fewer changes after 0.02%. Replacement of the aqueous humor with 0.02% thymoxamine caused no effect on either the corneal endothelium or ciliary process, whereas 0.2% caused small, but significant, changes in both tissues.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Endotélio Corneano
/
Corpo Ciliar
/
Moxisilita
Limite:
Animals
Idioma:
En
Revista:
Lens Eye Toxic Res
Ano de publicação:
1990
Tipo de documento:
Article