Pseudotumor of the tracheal-laryngeal junction with unusual morphologic features caused by Rhodococcus equi infection.
Head Neck Pathol
; 5(4): 395-400, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-21519873
ABSTRACT
Infectious pseudotumors are unusual proliferations of histiocytes in response to certain microbial organisms. Occasionally this process may involve large airways, producing a mass lesion that may cause respiratory obstruction. Infectious pseudotumors can be confused with malignancy in their radiologic appearance and clinical presentation. We present a case of an aggressive endotracheal pseudotumor associated with Rhodococcus equi infection in a patient with advanced HIV disease. Microscopically, the lesion was composed of sheets of epithelioid histiocytes with large, strongly eosinophilic intra-cytoplasmic granules and features of malakoplakia. In this report, we review the literature of these unusual lesions and compare them to cases of conventional malakoplakia involving the large airways. We also explore the pathogenetic mechanisms that may contribute to the distinctive histologic appearance of Rhodococcus-associated pseudotumors.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traqueia
/
Infecções por Actinomycetales
/
Rhodococcus equi
/
Laringe
/
Malacoplasia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Head Neck Pathol
Ano de publicação:
2011
Tipo de documento:
Article