[Steatohepatitis after chemotherapy for colorectal liver metastases (CASH)]. / Steatohepatitis bei der Chemotherapie kolorektaler Lebermetastasen (CASH).
Pathologe
; 32(4): 330-5, 2011 Jul.
Article
em De
| MEDLINE
| ID: mdl-21681471
ABSTRACT
Neoadjuvant chemotherapy provides an important treatment option for patients who, as a consequence of colorectal cancer, have developed liver metastases. Regression of metastases prior to surgery may substantially improve prognosis. However, chemotherapeutics may harm non-tumorous liver tissue, particularly if this is already impaired prior to chemotherapy. The present article discusses the risks of chemotherapeutics for liver tissue-including sinusoidal obstruction syndrome, nodular regenerative hyperplasia, and chemotherapy-associated steatohepatitis, amongst others-which should be borne in mind when selecting therapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Terapia Neoadjuvante
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Fígado Gorduroso
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Neoplasias Hepáticas
/
Antineoplásicos
Limite:
Humans
Idioma:
De
Revista:
Pathologe
Ano de publicação:
2011
Tipo de documento:
Article