A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion.

Harterink, Martin; Port, Fillip; Lorenowicz, Magdalena J; McGough, Ian J; Silhankova, Marie; Betist, Marco C; van Weering, Jan R T; van Heesbeen, Roy G H P; Middelkoop, Teije C; Basler, Konrad; Cullen, Peter J; Korswagen, Hendrik C

Harterink, Martin; Port, Fillip; Lorenowicz, Magdalena J; McGough, Ian J; Silhankova, Marie; Betist, Marco C; van Weering, Jan R T; van Heesbeen, Roy G H P; Middelkoop, Teije C; Basler, Konrad; Cullen, Peter J; Korswagen, Hendrik C.

Afiliação

Harterink M; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
Port F; Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Lorenowicz MJ; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
McGough IJ; Henry Wellcome Integrated Signaling Laboratories, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
Silhankova M; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
Betist MC; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
van Weering JRT; Henry Wellcome Integrated Signaling Laboratories, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
van Heesbeen RGHP; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
Middelkoop TC; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
Basler K; Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Cullen PJ; Henry Wellcome Integrated Signaling Laboratories, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom.
Korswagen HC; Hubrecht Institute, Royal Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

Nat Cell Biol ; 13(8): 914-923, 2011 Jul 03.

Article em En | MEDLINE | ID: mdl-21725319

Assuntos

Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Nexinas de Classificação/metabolismo; Proteínas Wnt/metabolismo; Animais; Animais Geneticamente Modificados; Transporte Biológico Ativo; Caenorhabditis elegans/genética; Caenorhabditis elegans/crescimento & desenvolvimento; Caenorhabditis elegans/metabolismo; Drosophila/genética; Drosophila/crescimento & desenvolvimento; Drosophila/metabolismo; Endossomos/metabolismo; Células HeLa; Humanos; Modelos Biológicos; Interferência de RNA; Transdução de Sinais; Nexinas de Classificação/antagonistas & inibidores; Nexinas de Classificação/genética; Rede trans-Golgi/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Wnt / Nexinas de Classificação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2011 Tipo de documento: Article

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