¹H, ¹³C, ¹5N and ³¹P chemical shift assignments of a human Xist RNA A-repeat tetraloop hairpin essential for X-chromosome inactivation.
Biomol NMR Assign
; 6(1): 75-7, 2012 Apr.
Article
em En
| MEDLINE
| ID: mdl-21779925
ABSTRACT
Initiation of X-chromosome inactivation in female mammals depends on the non-coding RNA Xist. We have solved the NMR structure of a 14-nucleotide hairpin with a novel AUCG tetraloop fold from a Xist A-repeat that is essential for silencing. The (1)H, (13)C, (15)N and (31)P chemical shift assignments are reported.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ressonância Magnética Nuclear Biomolecular
/
RNA não Traduzido
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Cromossomos Humanos X
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Inativação do Cromossomo X
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Sequências Repetidas Invertidas
Limite:
Humans
Idioma:
En
Revista:
Biomol NMR Assign
Ano de publicação:
2012
Tipo de documento:
Article