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Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus).
Palacios, Gustavo; Wellehan, James F X; Raverty, Stephen; Bussetti, Ana V; Hui, Jeffrey; Savji, Nazir; Nollens, Hendrik H; Lambourn, Dyanna; Celone, Christopher; Hutchison, Stephen; Calisher, Charles H; Nielsen, Ole; Lipkin, W Ian.
Afiliação
  • Palacios G; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Wellehan JFX; Marine Animal Disease Laboratory, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
  • Raverty S; Animal Health Center, Abbotsford Agriculture Centre, Provincial Government of British Columbia, Abbotsford, British Columbia, Canada.
  • Bussetti AV; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Hui J; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Savji N; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Nollens HH; Marine Animal Disease Laboratory, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
  • Lambourn D; Marine Mammal Investigations, Washington Department of Fish and Wildlife, Washington, USA.
  • Celone C; 454 Life Sciences, Branford, CT, USA.
  • Hutchison S; 454 Life Sciences, Branford, CT, USA.
  • Calisher CH; Arthropod-borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
  • Nielsen O; Department of Fisheries and Oceans Canada, Winnipeg, Manitoba, Canada.
  • Lipkin WI; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
J Gen Virol ; 92(Pt 11): 2558-2565, 2011 Nov.
Article em En | MEDLINE | ID: mdl-21795475
ABSTRACT
An aborted mid-gestational male Steller sea lion fetus with an attached placenta was recovered on the floor of an open floating capture trap located off Norris Rock near Denman Island, British Columbia. Viral culture of the placenta demonstrated cytopathic effect. Although no specific signal was obtained in microarray experiments using RNA obtained from viral culture, elution and sequence analysis revealed the presence of a reovirus. Complete genome pyrosequencing led to the identification of an orthoreovirus that we have tentatively named Steller sea lion reovirus (SSRV). Phylogenetic analysis revealed similarities between SSRV and orthoreoviruses of birds, bats and other mammals that suggests potential for interspecies transmission.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Viral / Genoma Viral / Orthoreovirus / Feto Abortado / Leões-Marinhos Limite: Animals / Pregnancy País/Região como assunto: America do norte Idioma: En Revista: J Gen Virol Ano de publicação: 2011 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Viral / Genoma Viral / Orthoreovirus / Feto Abortado / Leões-Marinhos Limite: Animals / Pregnancy País/Região como assunto: America do norte Idioma: En Revista: J Gen Virol Ano de publicação: 2011 Tipo de documento: Article